Older Whooping Cough Vaccine May Actually Deliver Longer Protection

Older Whooping Cough Vaccine May Actually Deliver Longer Protection

Jul 09 2018

Researchers at La Jolla Institute for Allergy and Immunology (LJI) reported today that individuals who had been inoculated with the newer pertussis vaccine mount a weaker recall response when receiving booster shots later on.

Traditionally the ability to induce a high antibody titer has been the yardstick against which vaccines have been measured.

"We see a dramatic imprinting effect depending on whether people received the old or the new pertussis vaccine as part of their original childhood immunizations," says the study's senior author LJI professor Alessandro Sette, Dr. Biol. Sci., head of the Division of Vaccine Discovery, in a press release.

"Even if the booster shots they received as middle and high schoolers or as adults contained the same vaccine the immune system still has a very striking recollection of what it saw during the first immunization."

Source: Precision Vaccinations Precision Vaccinations