Study: Vaccine Suppresses Peanut Allergies in Mice

Study: Vaccine Suppresses Peanut Allergies in Mice

Apr 11 2018

Just three monthly doses of a nasal vaccine protected the mice from allergic reactions upon exposure to peanut, according to research from the Mary H. Weiser Food Allergy Center at the University of Michigan.

U-M researchers have spent nearly two decades developing a vaccine agent and have recently translated this work to the development of a vaccine to treat food allergies. In the new study, immunizing peanut allergic mice can redirect how immune cells responded to peanuts in allergic mice.

The new approach activates a different type of immune response that prevents allergic symptoms.

“We’re changing the way the immune cells respond upon exposure to allergens,” says lead author Jessica O’Konek, Ph.D., a research investigator at the food allergy center. “Importantly, we can do this after allergy is established, which provides for potential therapy of allergies in humans.”

Source: U of M Health U of M Health